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| Spec | Focusrite Scarlett 2i2 4th Gen | PreSonus StudioLive AR8c |
| General | ||
| Category | Mid-Range | Mixer-Type |
| Reference Price (USD) | 225 | 500 |
| Supported OS | iOS/macOS/Windows | macOS/Windows |
| Connection | USB 2.0 | USB 2.0 |
| Inputs | ||
| Mic Preamps | 2 | 4 |
| Combo Inputs (XLR/TRS) | 2 | 4 |
| Line Inputs | — | 4 |
| Hi-Z Inputs | — | 2 |
| ADAT Input (ch@48kHz) | — | — |
| Optical Ports (Input) | — | — |
| S/PDIF (Coax) Input | — | — |
| S/PDIF (Optical) Input | — | — |
| AES/EBU Input | — | — |
| Outputs | ||
| Analog Main Output | 2 | 2 |
| Analog Line Output | — | — |
| Headphone Output | 1 | 1 |
| ADAT Output (ch@48kHz) | — | — |
| Optical Ports (Output) | — | — |
| S/PDIF (Coax) Output | — | — |
| S/PDIF (Optical) Output | — | — |
| AES/EBU Output | — | — |
| Features | ||
| Phantom Power (48V) | Yes | Yes |
| MIDI I/O | Yes | — |
| Loopback | Yes | — |
| DSP Effects | Yes (Built-in) | Yes (Built-in) |
| Direct Monitoring | Yes | Yes |
| Audio Performance | ||
| Max Sample Rate (kHz) | 192 | 96 |
| Max Bit Depth (bit) | 24 | 24 |
| Preamp Gain Range (dB) | 69 | — |
| DR Input (dB, A-weighted) | — | — |
| DR Output (dB, A-weighted) | — | — |
| DR (Unknown Conditions) | 120 | — |
| THD+N Mic Input (dB(%), 1kHz) | — | — |
| THD+N Output (dB(%), 1kHz) | — | — |
| THD+N (dB(%), Unknown) | — | — |
| EIN (dBu, A-weighted) | — | — |
| EIN (dBu, Unknown) | — | — |
| Software & Other | ||
| Bundled Software | Ableton Live Lite, Pro Tools Intro | Studio One Artist, Studio Magic Plugin Suite |
| Notes | 120d B dynamic range | 8ch analog mixer+USB IF, XMAX preamp, 3-band EQ, Bluetooth, SD card recording |